The Michael Shermer Show
The Michael Shermer Show

216. Kathryn Paige Harden — The Genetic Lottery: Why DNA Matters for Social Equality

In recent years, scientists have shown that DNA makes us different, in our personalities and in our health — and in ways that matter for educational and economic success in our current society. Michael speaks with University of Texas (Austin) professor of clinical psychology and Director of the Deve

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Catherine Paige Harden Guest

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Episode Summary

Executive Summary: Michael Shermer and Catherine Paige Harden discuss how genetics influences complex human traits without implying destiny or moral hierarchy. The conversation covers heritability, twin studies, GWAS/polygenic scores, education, social policy, equality of opportunity, and why genetic findings do not justify racism, determinism, or reduced rights.

Main Topics: Genes, temperament, and social behavior: Harden explains that genes shape basic temperaments and personality dispositions, which are then expressed through social choices and available environments, rather than encoding specific beliefs or behaviors like politics or religion. Behavior genetics and heritability: The discussion centers on the three laws of behavior genetics, twin studies, and the meaning of heritability—emphasizing that genetic influence is real, but probabilistic and context-dependent. Education, Head Start, and policy evaluation: They explore what counts as educational 'success,' the mixed evidence on interventions, and how genetics can improve environmental research by helping isolate which interventions actually matter. Gender, work, and prestige hierarchies: Harden argues that sex differences in occupational choices should be interpreted in light of social constraints and how society values different kinds of labor, not just individual preferences. Race, IQ, and misuse of genetics: The conversation rejects the leap from heritability to racial hierarchy, criticizing arguments like those associated with Charles Murray and emphasizing historical racism and unequal environments. Equality, social justice, and reparations: They debate equality of opportunity versus outcomes, with Harden stressing broader material security, health, dignity, and systemic remediation over narrow meritocratic competition. Epigenetics and future research: Harden clarifies that epigenetics complements genetics rather than replacing it, and she previews future 'double lottery' studies combining genetic and environmental randomization.

Key Arguments: Genetic influence on behavior does not mean there is a 'gene for' a specific social identity or belief; genes shape temperament, which interacts with social structures. Heritability is not a fixed share of a trait caused by genes; it is population- and context-specific and often increases when people increasingly select their own environments. Twin and adoption studies show that genetics matter, but they also reveal that shared family environment can still affect some outcomes, especially years of education. Polygenic scores summarize tiny effects across many variants and can predict some outcomes, but they are probabilistic, population-specific, and limited in portability across ancestries. Education interventions can work, especially early childhood programs, but many later interventions show little average effect; success depends on what outcome is measured. The fact that one group has a lower score or outcome in one environment does not mean the cause is genetic; different environments can produce the same phenotype or different ones. Equal opportunity should mean more than identical treatment; it may require accommodation, resources, and structural support so people can actually participate as equals. Rights and moral worth do not depend on IQ, genetics, group averages, or how common a trait is; ethical commitments must be defended independently of empirical findings. Genetics can inform better policy by revealing heterogeneity in responses to interventions and by improving environmental research, not by ranking human value. Racial disparities in outcomes are best understood through historical and environmental legacies such as slavery, redlining, environmental racism, and lead exposure.

Data Points: Book title: The Genetic Lottery: Why DNA Matters for Social Equality - Shermer introduces Harden and the book framing the conversation. Behavior genetics laws: 3 laws - Shermer asks Harden to explain Eric Turkheimer’s three laws of behavior genetics. Age pattern of heritability: Adult > adolescence > childhood - Harden notes that heritability estimates often increase with age as people select environments. GWAS sample size: 1.5 million people - Harden cites a recent study pooling data on 1.5 million people. Genetic markers measured: Hundreds of thousands of variants - Harden describes genome-wide association studies across the genome. Study duration/complexity: 12,000 variables over 12 years - She describes a prediction challenge using birth-to-age-12 data. Teams in prediction study: 160 teams - Different research teams tried to predict child outcomes at age 15. Variance explained in prediction study: No more than 20% - Even with extensive data, teams could not explain more than 20% of variation in age-15 outcomes. Educational inequalities left unexplained: More than 75% - Shermer quotes Harden that eliminating major measured inequalities would still leave most educational variance unexplained. Educational inequality reduced by controls: A bit more than a quarter - Harden’s quoted claim about how much variance in educational outcomes would be removed by controlling major visible inequalities. Texas COVID learning loss estimate: 4 years - Harden says Texas estimated children would take about four years to catch up in math after COVID disruptions. Plumber vs assistant professor salary comparison: Median plumber salary higher than first-year assistant professor of English - Used to argue prestige hierarchies often obscure economic value of labor. Maternal mortality context: One of the highest maternal mortality rates in the high-income world - Harden criticizes Texas for maternal health outcomes.

Pivotal Quotes: "We know that divorce is heritable." — Catherine Paige Harden: Used to explain that genetic influence can shape socially constructed outcomes like divorce through temperament and relationship patterns. "It would assert that the most important difference between the races is racism... Opposition to determinism, reductionism, and racism... need not depend on blanket rejection of undeniable, if easily misinterpreted, heritability." — Eric Turkheimer (quoted by Shermer): Shermer reads from the 'psychometric left' framing to show how one can accept genetic effects without endorsing racism. "The more uniformly beneficial the climate, the more pronounced the effects of genetic difference." — Catherine Paige Harden: Discussed in relation to how environment and genetics interact, and why equal or improved conditions can reveal genetic variation.

Implications: The episode argues for using genetics as a tool to improve policy and science, not to justify hierarchy. For listeners, the key takeaway is that fairness requires both empirical rigor and moral commitments beyond IQ or heritability.

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