Hidden Brain
Hidden Brain

Episode 32: The Scientific Process

Lots of psychology studies fail to produce the same results when they are repeated. How do scientists know what's true?

Featured Speakers

Shankar Vedantam Host

Topics Discussed

Episode Summary

Executive Summary: The episode examines the so-called replication crisis in science, arguing that failed replications often reveal nuance rather than fraud. Using psychology examples—especially the Asian women/math stereotype study—it shows how different labs can get different results due to context, design, and randomness, and why science advances by accumulating evidence rather than delivering final truth.

Main Topics: The replication crisis in science: The episode introduces widespread concern that many published findings, especially in psychology and medicine, do not hold up when independently repeated. Examples of controversial and flawed studies: Cases like broken sidewalks and racism, gay contact reducing anti-gay bias, and the bilingual advantage are used to show how some celebrated findings were later undermined by fraud, retraction, or incomplete reporting. Why reproducibility matters: Brian Nosek explains that a scientific claim becomes credible when other researchers can reproduce it using the same protocol and procedures. The Asian women and math stereotype study: Todd Patinsky and Margaret Shee’s study found that reminding Asian American women of gender hurt math performance, while reminding them of Asian identity improved it; it became a famous stereotype-threat/stereotype-boost example. Competing replications and contextual differences: Replications at Georgia Southern and UC Berkeley produced different outcomes, raising questions about location, experimenter gender, and whether the studies were truly identical. What failed replication really means: Experts argue that replication is not primarily a fraud detector; different results can reflect sample size, randomness, moderators, or boundary conditions rather than invalid science. Science as cumulative, probabilistic knowledge: The episode concludes that science is about building more precise estimates over time, not finding permanent final answers.

Key Arguments: Many high-profile findings in psychology and adjacent fields have not replicated, which has prompted concern about the reliability of published science. Some failures stem from outright fraud or retracted papers, but others reflect incomplete reporting, selective publication, or differences in context rather than deception. A study becomes more credible when independent researchers can reproduce it with similar methods and similar results. Exact replication is often unrealistic in social science because small procedural changes, location, population, and experimenter characteristics can alter outcomes. Different replication results do not automatically mean the original study was false; they may indicate effect-size overestimation, randomness, or important moderating variables. Replication should be used to refine understanding and estimate the size and conditions of effects, not only to expose misconduct. Science is incremental: each study is one data point, and truth emerges from many dots over time rather than a single decisive experiment.

Data Points: Studies replicated in OSC project: 100 - Psychology experiments the Center for Open Science recruited teams around the world to replicate Replication success rate: less than half - Brian Nosek reported reproducing original results in fewer than half of cases across five criteria Year of replication report: 2015 - Nosek’s large replication effort was published that year Broken sidewalks study year: 2011 - Dutch researchers published the claim that broken sidewalks encourage racism Gay marriage contact study year: 2009 - A Science paper claimed that personal contact with a gay person could change anti-gay-marriage views Bilingual advantage experiments: 4 - The paper had four experiments, but only one showed a benefit and only that one was published Experiments showing bilingual advantage: 1 - Only one of four experiments supported the claim Harvard replication sites: 2 - The Asian women/math study was replicated at Georgia Southern University and UC Berkeley Original study publication year: 1999 - The stereotype/Asian women math finding became a textbook example after publication SAT prep example effect sizes: 15% vs 3% - Eric Bradlow used this to explain how different studies may vary yet still support a real effect Mice recovery times: 35 minutes vs 16 minutes - NIH example showing how cage wood shavings affected sedation recovery time

Pivotal Quotes: "One of the key factors of science is that a claim becomes a credible claim by being reproducible." — Brian Nosek: Explaining why replication is central to scientific credibility "Science is the slow march of accumulating evidence." — Brian Nosek: Describing replication as an ongoing process of refinement rather than a final verdict "If you want answers that never change, definitive conclusions, and final truths, odds are you don't want to ask a scientist." — Shankar Vedantam: Concluding the episode’s view of science as probabilistic and evolving

Implications: Listeners should treat scientific findings as provisional and context-dependent. For research and publishing, the episode supports preregistration, more replications, and better incentives for careful, cumulative science.

From the Episode

Something had to be done. Brian felt the problem was that too many researchers and too many scientific journals were focusing on publishing new and unusual findings. Too few were spending time cross-checking earlier work to make sure it was solid. One of the key factors of science is that a claim becomes a credible claim by being reproducible. That someone else can take the same approach, the same protocol, the same procedure, do it again themselves. And obtain a similar result. Brian launched an effort to reproduce dozens of studies in psychology. He published a report in 2015. We found that we were able to reproduce the original results in less than half of the cases across five different criteria of evaluating whether a replication was successful or not. Over the last year, there have been many debates about what this means. Some critics say it proves that most studies are worthless. At many universities, researchers feel it's their

Brian Nosek · at 3:12

Published, it's not because I did anything fraudulent, just isn't true because of sample size, the way I collected the data, then you know what? Science will eventually figure out that what I'm saying is not true. So, if you'd like to Brian Nozek is bemused, that his findings about replicability have been taken to mean that the studies that fail to reproduce are worthless. He started a new system where researchers register protocols for their studies and commit to sticking to them. Scientific journals commit to publishing the findings of these studies, regardless of whether the Science is the slow march of accumulating evidence. And it's very easy to want a simple answer. Is it true or is it false? But really, replication is just an opportunity to accumulate more evidence to get a more precise estimate of that particular effect. To most people, the debate over scientific truth is an abstract issue. Most of us turn to scientists for answers. Should I drink a glass of red wine in the evening? Is this drug safe to give to my ailing mother? Should I give my kid a dollar every time she does something well at school? In reality, science is more in the question business than the answer business. There's a reason nearly every scientific paper ends with a call for more research. Especially when it comes to human behavior.

Brian Nosek · at 25:00

Nearly every conclusion you can draw about human beings has tons of exceptions. Are people selfish? Yeah, except millions act altruistically every day. Are humans kind? Yes, except that few species are capable of greater cruelty. If you want answers that never change, definitive conclusions and final truths, odds are you don't want to ask a scientist. The Hidden Brain podcast is produced by Kara McGurk-Allison, Maggie Penman, and Max Nestrak. You can follow us on Facebook, Twitter, and Instagram, and follow my stories on your local public radio station. If you like this episode, consider giving us a review on iTunes. It will help other people find the podcast. I'm Shankar Vedantam, and this is NPR. Thanks for listening to Hidden Brain. If you haven't already, please try the NPR1 app for your phone. You can hear Guy Raza's interview with TED curator Chris Anderson, where they discuss the art of public speaking. You can search for shows, find stories from your local station, and listen to great podcasts. NPR1 is in the app store now. Also, Invisibilia Season 2 returns on June 17th. This season, the show goes to a prison, an oil rig, a McDonald's in Russia, and a beach in New Jersey to explore.

Shankar Vedantam · at 26:20
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Why do I feel stuck? How can I become more creative? What can I do to improve my relationships? If you’ve ever asked yourself these questions, you’re not alone. On Hidden Brain, we help you understand your own mind — and the minds of the people around you. (We're routinely rated the #1 science podcast in the United States.) Hosted by veteran science journalist Shankar Vedantam.

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