The School of Greatness
The School of Greatness

Has The Medical System Betrayed Women? How To Take Back Control of Your Health

Three pioneering female doctors reveal how women's health has been systematically overlooked in medicine and share groundbreaking solutions for menopause, epigenetic aging, and mental wellness. Dr. Mary Claire Haver, Dr. Rhonda Patrick, and Dr. Caroline Leaf provide essential insights on hormon

Featured Speakers

Lewis Howes Host

Topics Discussed

Episode Summary

Executive Summary: The episode spans three major themes: a promotion for Lewis Howes’ book/podcast tour, a deep discussion on menopause as an under-researched and undertreated health transition for women, and a long-ranging conversation on longevity, sleep, supplements, and mental health. The guests argue for education, lifestyle optimization, and a more nuanced, less stigmatizing approach to women’s health and emotional suffering.

Main Topics: Book and podcast tour promotion (Priority: 2/5): Lewis Howes opens by promoting his new book Make Money Easy and a seven-city tour tied to the podcast and live events. Menopause as a neglected medical issue (Priority: 5/5): The conversation argues that women’s health, especially menopause, has been historically under-studied and poorly treated, with women often receiving antidepressants instead of hormone therapy. Hormone therapy vs. standard treatment (Priority: 5/5): The guests contrast hormone replacement therapy with SSRIs/SNRIs and emphasize that HRT is often the more appropriate gold-standard option when clinically indicated. Men’s role in supporting women through menopause (Priority: 4/5): There is a strong emphasis on educating male partners so they can respond with empathy, understanding, and practical support rather than confusion or dismissal. Longevity, aging biology, and epigenetic reprogramming (Priority: 4/5): The discussion shifts to cutting-edge aging science, including epigenetic clocks, Yamanaka factors, and the idea that aging may be programmable and potentially reversible. Sleep, exercise, nutrition, and supplements for healthspan (Priority: 4/5): A detailed ‘optimal day’ routine is laid out, prioritizing morning light, exercise, sauna/cold exposure, time-restricted eating, protein, omega-3s, vitamin D, and other supplements. Mental health, trauma, and the neurocycle model (Priority: 5/5): The transcript concludes with a critique of disease labels for trauma-related distress and an explanation of a stepwise neurocycle method for regulating emotions and processing traumatic events.

Key Arguments: Women were historically excluded from research; this has created a medical system that often extrapolates male data to female bodies. Menopause is not just hot flashes: it is tied to rising cardiovascular risk, insulin resistance, cholesterol changes, and broad quality-of-life effects. Statins are widely prescribed to women even though evidence cited here says they have not been shown to reduce heart attack or death risk in women in the same way they do in men. Most women who report menopausal symptoms are not offered HRT; the guests say the current default is often an antidepressant, despite HRT being the gold standard for many patients. Male partners should educate themselves and support women through menopause by understanding it as an inevitable life stage rather than a personal failing. Aging may be more of a biological program than simple damage accumulation, and epigenetic reprogramming may one day make rejuvenation possible. Exercise, sleep, light exposure, and nutrition are repeatedly framed as foundational longevity interventions that can’t be replaced by supplements alone. Trauma and anxiety should not always be framed as disease; they can be meaningful responses to adverse experiences that require processing rather than simple labeling.

Data Points: NIH legal requirement for women in studies: 1993 - Women were not legally required to be included in studies until 1993. Women offered treatment after reporting menopausal symptoms: 10% - Only about 10% of women who mention typical menopause symptoms are offered treatment. Women currently on HRT: 4% to 6% - The speaker says only a small fraction of menopausal women are on hormone replacement therapy. Increased cardiovascular disease risk after menopause: 50% - A postmenopausal 50-year-old woman is described as having about a 50% increased heart disease risk compared with a premenopausal peer. HRT cardiovascular benefit if started early: 50% per year - The guest claims early hormone therapy can decrease cardiovascular disease risk substantially when started in time. Average menopause age: 51 - Average age given for menopause, when periods stop. Normal menopause age range: 45 to 55 - The discussion describes this as a normal range, with perimenopause lasting 7 to 10 years. Perimenopause education starting age: Around 35 - The guest argues patients should start being educated and screened in their 30s. Average menopause timing for most women: 95% through by age 55 - The speaker says most women complete menopause by 55. Earlier menopause linked to childhood sexual abuse across generations: 9 years earlier - A cited study found menopause occurred nine years earlier in women with that trauma history. Life expectancy gain with higher omega-3 index: 5 years - People with an 8% omega-3 index are described as having about a 5-year longer life expectancy than those with low levels. U.S. average omega-3 index: 5% - The speaker says the average U.S. omega-3 index is around 5%. High omega-3 index example: 8% - Used as a comparison point for a higher-risk-reducing level. Japan average omega-3 index: 10% - Cited as one reason Japan may have longer average lifespan than the U.S. One supplement target claim: 2 grams/day omega-3 - The speaker says this amount can raise omega-3 index substantially over a few months. Supplements if limited to three: Omega-3, vitamin D, sulforaphane - The guest names these as the three most essential supplements. Supplements if limited to five: Omega-3, vitamin D, sulforaphane, magnesium, multivitamin - Expanded top-five recommendation. Neurocycle benefit claim: 81% improvement - The trauma-regulation method is said to improve anxiety and depression management by 81%.

Pivotal Quotes: "“This should be required in medical school.”" — Guest discussing women’s health: A call for mandatory menopause and sex-differences training for all clinicians who treat women. "“This is an inevitable process, but suffering through it is not.”" — Guest on menopause: Core takeaway meant to reduce fear and encourage support, education, and treatment. "“Exercise is the longevity drug that if you could pill it up, we'd all be taking it.”" — Longevity guest: A summary of the episode’s healthspan philosophy, elevating exercise above most interventions.

Implications: Listeners are urged to treat menopause, longevity, and trauma as actionable health challenges: seek education, prioritize exercise/sleep/nutrition, and support women with informed care. The medical system may need major reform, especially around sex-specific research and mental health framing.

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About The School of Greatness

Lewis Howes is a New York Times best-selling author, 2x All-American athlete, keynote speaker, and entrepreneur. The School of Greatness shares inspiring interviews from the most successful people on the planet—world-renowned leaders in business, entertainment, sports, science, health, and literature—to inspire YOU to unlock your inner greatness and live your best life.

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