The School of Greatness
The School of Greatness

How Your Brain Is Hurting or Helping Your Relationships, Memory & Life w/Dr. Daniel Amen (PART 2) EP 1121

“If it’s good for your heart, it’s good for your brain.” Today's guest is Dr. Daniel Amen, who has helped millions of people transform their lives and brains through Amen Clinics, his best-selling books, and public television programs. The Washington Post has called Dr. Amen “the most popular p

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Lewis Howes Host

Episode Summary

Executive Summary: Dr. Daniel Amen argues that most psychiatric problems are brain health problems, not “mental illnesses,” and that better outcomes come from combining brain imaging, lifestyle changes, and targeted interventions. The conversation covers Bright Minds factors—exercise, immunity, hormones, diabetes, sleep, toxins, and more—plus relationships, memory, dopamine, marijuana, trauma treatments, and practical habits for protecting cognition and emotional stability.

Main Topics: Brain health vs. mental illness framing (Priority: 5/5): Amen argues psychiatry should be rooted in biological brain data, not symptom clusters, and that reducing stigma by calling problems brain illnesses improves treatment adherence and outcomes. Bright Minds framework (Priority: 5/5): He outlines a holistic model for optimizing brain function through exercise, immunity/infections, neurohormones, diabetes/blood sugar, sleep, toxins, and related behaviors. Dopamine, addiction, and modern overstimulation (Priority: 5/5): Amen warns that constant high-intensity dopamine hits from phones, drugs, pornography, sugar, and some behaviors can wear out pleasure centers and increase addiction risk. Brain health, relationships, and marriage (Priority: 4/5): He explains how brain patterns shape partner choice and conflict style, and says better brain function can improve communication, attachment, and long-term relationship stability. Memory, aging, and cognitive training (Priority: 4/5): Amen stresses that memory training and new learning help preserve cognition, especially in an age where devices replace active remembering. Trauma treatment and brain-based therapies (Priority: 4/5): He discusses EMDR, havening, and other approaches that help process trauma by engaging emotional circuits and calming them without relying solely on medication. Controversial substances and brain risk (Priority: 4/5): Amen critiques marijuana, vaping, and unmanaged consciousness-altering substances, while acknowledging some therapeutic uses for cannabis, ketamine, and psychedelics under supervision.

Key Arguments: Psychiatric problems are brain illnesses; using biological data and imaging leads to better diagnosis and reduces stigma. Exercise, gratitude, and healthy habits can be as effective as medication for some conditions, including depression. Infections and immune issues can contribute to psychiatric symptoms; Lyme disease may mimic or worsen serious mental illness in some cases. COVID-19 can affect the brain and is associated with anxiety, depression, brain fog, and long COVID symptoms. Vitamin D optimization is emphasized as a practical immunity and brain-health strategy. Low testosterone and other hormonal imbalances can contribute to depression, anxiety, and low energy. Diabetes and prediabetes damage the brain, shrink it over time, and harm hippocampal function. Sleep is essential because the brain’s cleaning system activates during sleep; poor sleep increases depression, fog, and dementia risk. Overstimulation of dopamine receptors from drugs, pornography, alcohol, and digital media can flatten pleasure and contribute to addiction. Marijuana is presented as a brain-aging risk factor; Amen says it is not benign even if it may help specific medical conditions. New learning, such as language study, is an effective way to build and preserve memory and cognitive resilience. Better brain health improves relationships because people repeat learned conflict patterns unless they intentionally retrain them.

Data Points: Brain scans collected: Over 183,000 - Amen describes the size of his imaging database across 30 years of clinical work. Countries represented in scan database: 155 - Global scope of the Amon Clinics database. Clinic visit volume: Over 7,000 visits per month - Scale of his clinics' activity. Scientific studies published: 80 studies - Amen cites this as evidence supporting his approach. Scientific references on brain SPECT: 14,000 - He references the National Library of Medicine. COVID scans reviewed: About 50 - He mentions scanning patients affected by COVID-19. New-onset psychiatric diagnosis after COVID: About 20% - Amen says a fifth of people with COVID may develop anxiety/depression. Vitamin D suboptimal prevalence: About 80% - He says most people have less-than-ideal levels. Normal vitamin D range: 30 to 100 - Amen gives this reference range during the discussion. Cancer risk with vitamin D under 20: Double the risk - He cites a study linking low vitamin D to higher cancer risk. Population diabetic or pre-diabetic: 50% total (14% diabetic, 36% pre-diabetic) - Amen uses this to show the scale of metabolic brain risk. Brain blood flow share: 20% - He notes the brain consumes a disproportionate amount of blood flow. Brain calorie share: 30% - He says the brain uses a large share of daily calories. Annual hippocampal neuron loss/addition claim: 700 per day - He uses this to emphasize ongoing brain cell turnover and vulnerability. Dementia risk at age 85: 50% - He states that half of people age 85 will have dementia. Erectile dysfunction at age 40: 40% - He uses this as a marker for broader vascular/brain dysfunction. Schizophrenia vs Lyme disease geography: Virtually identical incidence maps - He argues infection screening should be considered in some psychiatric cases. Marijuana study sample: 1,000 pot smokers - Amen says imaging showed lower brain metrics compared with never-smokers. Largest aging imaging study: 62,454 scans - Used to compare brain aging trajectories and risk factors. Brain aging comparison: Schizophrenia about 10 years older than expected; marijuana next worst - Amen describes accelerated brain aging in his database. Sleep duration target: 6.5 to 8 hours nightly - He says insufficient sleep contributes to brain trash accumulation and mood problems. Long COVID duration: Not better in 3 days or even 6 months - Amen defines persistent symptoms by ongoing anxiety, brain fog, aches, etc. EMDR sessions in PTSD police study: Average of 8 sessions - He says officers returned to work after treatment. Podcast episodes: 847 - Amen references his show with his wife, The Brain Warrior’s Way.

Pivotal Quotes: "Psychiatric problems are not mental illnesses. They're brain illnesses." — Dr. Daniel Amen: Amen’s core reframing of psychiatry and stigma reduction. "Your brain is always listening." — Dr. Daniel Amen: The title idea of his book and the theme that habits, self-talk, and inputs shape brain health. "Drip dopamine, don't dump it." — Dr. Daniel Amen: His advice for preventing overstimulation and protecting reward circuitry.

Implications: Listeners are urged to treat brain health as foundational to mood, relationships, memory, and aging. The broader implication is a shift toward prevention, measurement, and lifestyle-based psychiatry rather than symptom-only treatment.

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About The School of Greatness

Lewis Howes is a New York Times best-selling author, 2x All-American athlete, keynote speaker, and entrepreneur. The School of Greatness shares inspiring interviews from the most successful people on the planet—world-renowned leaders in business, entertainment, sports, science, health, and literature—to inspire YOU to unlock your inner greatness and live your best life.

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