Episode Summary
Executive Summary: Lewis Howes and James Nestor explore how breathing habits shape health, performance, and longevity. Nestor argues that chronic mouth breathing, overbreathing, and poor oral posture contribute to respiratory illness, anxiety, sleep apnea, crooked teeth, and reduced oxygen efficiency, while nasal, slow, diaphragmatic breathing can improve CO2 balance, calm the nervous system, support immunity, and enhance athletic and aging outcomes.
Main Topics: Nose breathing vs. mouth breathing (Priority: 5/5): Nestor explains that nasal breathing filters, humidifies, and pressurizes air while also increasing nitric oxide and oxygen efficiency. Mouth breathing bypasses these protections and is linked to more illness, poorer sleep, and facial/jaw changes. CO2, breathing rate, and oxygen delivery (Priority: 5/5): A major thesis is that the urge to breathe is driven more by rising carbon dioxide than falling oxygen. Slow, less frequent breathing increases CO2 tolerance and can improve oxygen release to tissues and reduce overbreathing. Breathwork for anxiety, panic, and nervous system regulation (Priority: 5/5): The conversation highlights slow breathing, long exhales, box breathing, and breath-holds as tools to shift the body from sympathetic fight-or-flight into parasympathetic calm, helping manage panic and stress. Breathing, sleep apnea, and airway structure (Priority: 4/5): Nestor connects modern orthodontics, narrow mouths, soft diets, and poor oral posture to smaller airways, snoring, and sleep apnea. He discusses tongue posture and myofunctional therapy as part of airway improvement. Performance, athletics, and endurance (Priority: 4/5): The discussion covers nasal breathing during exercise, hypoventilation training, and controlled breathwork as methods to improve efficiency, endurance, and recovery without overtaxing the heart and lungs. Immunity, nitric oxide, and disease defense (Priority: 4/5): Nestor argues that nasal breathing and humming increase nitric oxide, which helps defend against pathogens and may support immune function. He frames breathing through the nose as a first line of defense against respiratory viruses. Longevity, lung capacity, and aging (Priority: 4/5): The episode closes with the idea that lung capacity predicts lifespan and that flexibility, airway health, and diaphragmatic function can be trained to preserve or expand respiratory health with age.
Key Arguments: Habitual mouth breathing is common but harmful because it bypasses the nose’s filtering, humidifying, and nitric-oxide-producing functions. The body’s need to breathe is driven largely by CO2 buildup, so overbreathing can worsen oxygen delivery and trigger panic-like symptoms. Slow, nasal, diaphragmatic breathing improves efficiency, circulation, and nervous-system regulation compared with chest breathing. Modern lifestyles, soft diets, orthodontic extractions, stress, and sedentary posture have contributed to smaller jaws and compromised airways. Breath training can help reduce symptoms for some people with asthma, anxiety, snoring, and sleep apnea, though it is not a replacement for medical care. Athletes can benefit from breathing less and more efficiently; elite training increasingly includes breathwork, nasal breathing, and CO2 tolerance drills. Nasal breathing and humming may help increase nitric oxide, which supports vasodilation and may help the body resist pathogens. Lung capacity and respiratory function are strongly tied to health span and longevity, and they can be improved through training and flexibility work.
Data Points: Habitual mouth breathers: 25% to 50% of the population - Nestor estimates the share of people who habitually breathe through the mouth. More oxygen from nasal breathing: 20% more oxygen - He claims equivalent breaths through the nose deliver more usable oxygen than mouth breathing. Breathing efficiency improvement: 35% - Slow, deep breathing is described as improving efficiency over shallow breathing. Nasal breathing rate in exercise experiment: 6 breaths per minute - Lewis describes a Stanford bike experiment using nasal breathing at this rate without dropping oxygen saturation. Nose cycle duration: 30 minutes to 3 or 4 hours - Nestor says one nostril naturally opens while the other closes on this cycle. Nasal nitric oxide advantage: 6 times more nitric oxide - He says breathing through the nose provides substantially more nitric oxide than mouth breathing. Nitric oxide boost from humming: 15-fold increase - Humming is said to raise nitric oxide significantly. Panic study outcome: 96% improved or very much improved - A study on slowing breathing and increasing CO2 among panic sufferers showed strong improvement after one year. Lung capacity loss with age: 15% to 16% decrease from ages 30 to 50 - He notes a typical decline in lung capacity during midlife. Average adult male lung capacity: About 6 liters - Used as a reference point when discussing freedivers and lung capacity gains. Potential lung capacity increase: About 30% - He says proper breathing and exercises can substantially increase capacity.
Pivotal Quotes: "Breathe through your nose all the time. I don't care if your nose is clogged." — James Nestor: He gives his core practical recommendation for daily breathing habits. "If you want to make your body a very violent place for viruses to live in, start with breathing through your nose, take your vitamin D, and C." — James Nestor: He summarizes his view of nasal breathing as an immune-defense practice. "Never underestimate the capabilities of your body." — James Nestor: One of his three closing truths about human potential and adaptation.
Implications: The episode frames breathing as a neglected health lever with implications for medicine, athletics, dentistry, sleep, and stress management. It suggests everyday nasal, slow, and diaphragmatic breathing could improve population health and performance at low cost.
About The School of Greatness
Lewis Howes is a New York Times best-selling author, 2x All-American athlete, keynote speaker, and entrepreneur. The School of Greatness shares inspiring interviews from the most successful people on the planet—world-renowned leaders in business, entertainment, sports, science, health, and literature—to inspire YOU to unlock your inner greatness and live your best life.