This Week in Startups
This Week in Startups

SNEAK PREVIEW: E2 All-In with Chamath Palihapitiya & Jason Calacanis: Rebooting the economy, understanding corporate debt, steps to avoid a depression & more with David Sacks

0:01 Jason & Chamath catch us up on their quarantines 1:20 Chamath intros David Sacks 4:40 David explains what their poker group chat has been like since COVID-19 started, and how Jason, Chamath & himself fall on the optimistic/pessimistic spectrum 6:58 How have the past few months defined D

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Jason Calacanis HostJason Calacanis GuestChamath Palihapitiya Guest

Topics Discussed

Episode Summary

Executive Summary: In this episode of the All-In Podcast, hosts Jason Calacanis and Chamath Palihapitiya interview David Sacks, a prominent entrepreneur and investor. They discuss the COVID-19 pandemic, critiquing government responses, the failure of institutions like the CDC and WHO, and the politicization of public health measures. The conversation covers the importance of masks, the controversy over hydroxychloroquine, and the need for decentralized decision-making and trust in experts. They also explore the economic implications and the role of incentives in shaping responses.

Main Topics: Government Response to COVID-19 (Priority: 5/5): Critique of federal and local government actions, including slow response, lack of unified strategy, and the impact of decentralization. Public Health Messaging and Trust (Priority: 5/5): Discussion on the CDC and WHO's misleading advice, particularly on masks, and the erosion of trust in institutions. Masks as a Simple Intervention (Priority: 4/5): Advocacy for widespread mask use as a low-cost, low-risk measure, contrasting with bureaucratic resistance. Hydroxychloroquine Controversy (Priority: 4/5): Debate over the drug's potential, politicization, and the need for 'right to try' approaches in treatment. Incentives and Modeling (Priority: 4/5): Analysis of how incentives drive modelers, media, and officials, leading to conservative or politicized forecasts. Economic Scenarios (V, U, L) (Priority: 3/5): Discussion of recovery shapes: V-shaped (optimistic), U-shaped (moderate), and L-shaped (pessimistic), with guest David Sacks swinging between U and L. Institutional Decline (Priority: 3/5): Critique of hollowed-out government institutions and the need for competent civil service, citing Singapore and South Korea.

Key Arguments: The decentralized U.S. system is both a blessing and a curse: it allows local innovation but hinders unified national strategy. Masks have zero downside and significant upside, yet authorities delayed recommending them due to political and reputational incentives. Hydroxychloroquine should be available for 'right to try' despite lack of conclusive evidence, as patients and doctors can make informed decisions. Modelers and officials are incentivized to be conservative or politicized, leading to inaccurate forecasts and delayed action. The hollowing out of government institutions over 40 years has led to incompetence and loss of public trust. Countries with strong civil services (e.g., Singapore, South Korea) handled the pandemic better than those with politicized bureaucracies.

Data Points: Doubling time of virus: Every 2-3 days - In absence of action, virus doubles every 2-3 days; in dense cities like NYC, possibly daily. Impact of one-week delay: 12x difference - If doubling time is 2 days, one week delay leads to 12x more cases, explaining NYC vs. California outcomes. Mask efficacy with cloth: 70% - A cloth mask can provide 70% efficacy in preventing droplet spread. Cost of mask: 10 cents - A cloth mask costs about 10 cents, making it a low-cost intervention. ICU capacity in New York: Sufficient - As of the podcast, Cuomo stated NYC has adequate ICU capacity and hospital beds.

Pivotal Quotes: "There's some decades when nothing happens, and there's some weeks where decades happen." — David Sacks (quoting Lenin): Describing the rapid change and impact of the pandemic. "We're taking the most draconian measure, quarantining people... but we won't do the basic thing of wearing the mask. It makes no sense." — Jason Calacanis: Highlighting the inconsistency in public health measures. "The incentives in those organizations are essentially to play their game, and that game is not one of public health, but it's one of politics." — Chamath Palihapitiya: Critiquing the CDC and WHO's motivations.

Implications: Listeners should question official narratives, prioritize low-risk interventions like masks, and recognize the role of incentives in shaping public policy. The pandemic exposes institutional weaknesses, urging a shift toward decentralized, experimental approaches and rebuilding trust in competent civil services.

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About This Week in Startups

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.

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